Akila, as to your specific question, if a writer chooses to use Word and has the patience to manually set the margins, I suppose the end result wouldn't be noticeable compared to a script created using a screenwriting software like Final Draft, Move Magic Screenwriter, or my personal favorite Fade In.
However, here's my question: Why not use software? If the issue is cost, the amount of time and hassle using Word as compared to a program like Fade In ($79.95), over time the software will more than pay for itself.
There are open source programs for free such as Trebly (https://www.trelby.org/), so there's really no excuse.
Then there's this: If you were to set up a project in Hollywood, you would have to have a Final Draft file, so eventually you'd have to do that anyway.